Wire- and magnetic-seed-guided localization of impalpable breast lesions: iBRA-NET localisation study

This IDEAL stage 2a/2b platform cohort study examined the effectiveness localisation and removal of the index lesion using wires vs. magnetic seeds. From 35 units, 2300 patients were recruited (Aug 2018-Aug 2020). Index lesion identification rate was 99.8% for magnetic seeds (n=946) and 99.1% for wires (n=1170). For patients undergoing breast conserving surgery for lesions <50mm (n=1746), there were no differences in median closest margin (2mm vs. 2mm), re-excision rate (12% vs. 13%), and specimen weight in relation to lesion size (0.15g/mm2 vs. 0.14g/mm2). Therefore, magnetic seed localisation demonstrated similar safety and effectiveness when compared to wire localisation.

Classifications: Breast & Oncoplastic Surgery

Keywords: Localisation